Celiac.com 04/21/2023 – When you’re attempting to shed extra pounds, you may need to take into consideration the quantity of gluten in your weight loss plan. A examine from 2015 discovered that wheat gluten consumption can contribute to weight acquire and fats accumulation, at the least in mice.
The examine sheds some gentle on the connection between gluten and weight acquire by investigating the consequences of gluten consumption on weight acquire, fats metabolism, and vitality expenditure in mice.
For the examine, researchers fed mice totally different diets for eight weeks. The diets included a control-standard weight loss plan, a regular weight loss plan with added wheat gluten, a high-fat weight loss plan, and a high-fat weight loss plan with added wheat gluten. Mice that had wheat gluten added to their diets gained extra weight, and had extra fats deposits, regardless of having the identical vitality consumption as mice within the management group.
Checks additionally discovered gluten within the blood, liver, and visceral adipose tissue, suggesting that it might attain organs past the intestinal tract. The examine discovered that gluten consumption lowered thermogenesis-related protein expression in subcutaneous and brown adipose tissues and lowered oxygen quantity consumption, which factors to lowered vitality expenditure.
Mice on a high-fat weight loss plan with added gluten additionally had decrease ranges of adiponectin, peroxisome proliferator-activated receptor (PPAR)-α and PPARγ, and hormone-sensitive lipase in cultures of remoted adipocytes. In contrast, in mice on a regular weight loss plan, added gluten consumption elevated interleukin-6 expression, and tended to extend tumor necrosis issue expression. This means that gluten might have totally different results on fats metabolism and irritation, relying on the weight loss plan.
Conclusions: Wheat Gluten Consumption Can Result in Elevated Weight Achieve and Fats Deposits
Total, the examine means that wheat gluten consumption can result in elevated weight acquire and fats deposits, together with lowered thermogenesis and vitality expenditure, particularly in mice on a high-fat weight loss plan.
The examine additionally highlights the potential systemic results of gluten, which might attain organs past the gut. Whereas the examine was performed in mice, the findings recommend that gluten might play a job in human weight acquire as effectively.
Whereas extra analysis is required to raised assess any connection between these findings and gluten consumption in people, the examine does provide some attention-grabbing meals for thought. Keep tune for extra on this and associated tales.
Learn extra at Int J Obes (Lond)